Application of PRP in the Treatment of Chronic Motor System Injury

A basic overview of chronic injuries of the motor system

Chronic injury of motor system refers to the chronic injury of the tissues involved in sports (bone, joint, muscle, tendon, ligament, bursa and related blood vessels and nerves) caused by local stress caused by long-term, repeated and continuous postures and occupational movements. It is a group of common clinical lesions. The pathological manifestations were hypertrophy and hyperplasia as compensation, followed by decompensation, slight tear, accumulation and delay. Among them, soft tissue chronic injury represented by tendinopathy and cartilage chronic injury represented by osteoarthritis are the most common.

When the human body has chronic diseases, or degenerative changes, can reduce the ability to adapt to stress; Local deformities can increase the local stress; Stress concentration can be caused by inattention at work, technical inproficiency, inaccurate posture, or fatigue, which are all causes of chronic injury. Workers in handicrafts and semi-mechanized industries, sports workers, theatrical and acrobatic performers, desk workers and housewives are all the most prone to this type of disease. To sum up, the incidence group is quite large. But chronic injuries can be prevented. The occurrence and recurrence should be prevented and combined with prevention and treatment to increase the efficacy. Single treatment does not prevent, symptoms often relapse, repeated author, treatment is very difficult. This DISEASE is caused by chronic injurious inflammation, so the key to the treatment is to limit the injurious action, correct the bad posture, strengthen the muscle strength, maintain the non-weight-bearing activity of the joint and change the posture regularly to disperse the stress.

Classification of chronic injuries of the motor system

(1) Chronic injury of soft tissue: chronic injury of muscle, tendon, tendon sheath, ligament and bursa.

(2) Chronic bone injury: mainly refers to the fatigue fracture in the bone structure is relatively fine and easy to produce stress concentration.

(3) Chronic injury of cartilage: including chronic injury of articular cartilage and epiphyseal cartilage.

(4) Peripheral nerve entrapment syndrome.

Clinical manifestations of chronic motor system injury

(1) Long-term pain in a part of the trunk or limb, but no obvious history of trauma.

(2) There are tender spots or masses in specific parts, often accompanied by some special signs.

(3) Local inflammation was not obvious.

(4) A recent history of hyperactivity related to the pain site.

(5) Some patients had a history of occupations and types of work that might cause chronic injury.

The role of PRP in chronic injury

Chronic tissue injury is a common and frequent disease in daily life. Traditional treatment methods have many disadvantages and side effects, and improper treatment will have a bad impact on the prognosis.

Platelets and various growth factors in PRP, as well as their interactions, have opened up new ideas in this field by providing an attachment point for cell adhesion, accelerating the physiological recovery process of tissues, alleviating pain, and providing anti-inflammatory and anti-infection functional properties.

Muscle strain is a common sports injury. Traditional treatment is based on physical therapy: such as ice, braking, massage and so on. PRP can be used as an adjuvant therapy for muscle strain due to its good safety and promoting cell regeneration.

Tendon is the transmission part of the movement system, which is prone to stress injury and chronic strain. Tendon tissue, which is made up of tendinocytes, fibrous collagen and water, lacks a blood supply of its own, so it heals more slowly after damage than other connective tissues. Histological studies of the lesions showed that the damaged tendons were not inflammatory, but that the normal repair processes, including fibrogenesis and vascularization, were limited. The scar tissue formed after tendon injury repair can also affect its function and may lead to tendon rupture again. Traditional treatment approaches tend to be long-term conservative and surgical for acute tendon rupture. The commonly used method of local glucocorticoid injection can help relieve symptoms, but can lead to tendon atrophy and structural changes. With further research, it was found that growth factors play a crucial role in the process of ligament repair, and then PRP was tried to promote or assist the treatment of tendon injury, with significant effect and strong response.

（The contents of this article are reprinted, and we do not provide any express or implied guarantee for the accuracy, reliability or completeness of the contents contained in this article, and are not responsible for the opinions of this article, please understand.）